Kidney Cancer Clinical Trials
Category:Adult
Status:Active
Displaying all 18 trials
A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma
CyberKnife Based Radiosurgery is a way to deliver large doses of radiation very accurately to a tumor. The ability of this technology to minimize radiation dose to organs adjacent to the target tum...
Diagnosis: Kidney Cancer
Phase: 2
Protocol Number: 12-235
Study of Atezolizumab + Bevacizumab in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma
This research study is studying the combination of Atezolizumab and Bevacizumab as a possible treatment for Advanced Non-Clear Cell Kidney Cancer.
Diagnosis: Kidney Cancer
Phase: 2
Protocol Number: 15-592
The purpose of this study is to assess the safety and efficacy of monotherapy pembrolizumab (MK-3475) in participants with renal cell carcinoma (RCC). There will be two cohorts in this study: Cohor...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 16-480
The main purpose of this study is to compare maintenance treatment with avelumab plus best supportive care (BSC) with BSC alone, to determine if avelumab has an effect on survival in patients with ...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 16-302
This is a single-arm, multicenter, Phase 2 study of lenvatinib in combination with everolimus in participants with unresectable advanced or metastatic non clear cell renal cell carcinoma (nccRCC) w...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-035
Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy
This randomized phase III trial compares nephrectomy (surgery to remove a kidney or part of a kidney) with or without nivolumab in treating patients with kidney cancer that is limited to a certain ...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-704
Study of TAK-228 In Patients With Previously Treated Metastatic Renal Cell Carcinoma
This research study is investigating a drug as a possible treatment for metastatic renal cell carcinoma. The intervention involved in this study is TAK-228.
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 16-527
This is a multicenter, randomized, open-label, Phase 3 study to compare the efficacy and safety of lenvatinib in combination with everolimus (Arm A) or pembrolizumab (Arm B) versus sunitinib (Arm C...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-038
This research study is studying two drugs at different time points as a possible treatment for advanced renal cell cancer The drugs involved in this study are: Nivolumab Ipilimumab
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-064
The purpose of this study is to evaluate the safety and efficacy of pembrolizumab (MK-3475) in the adjuvant treatment of adult participants who have undergone nephrectomy and have intermediate-high...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-267
A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma
The purpose of this study is to determine whether nivolumab in combination with other therapies is more effective than nivolumab in combination with ipilimumab in treating patients/subjects with ad...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-084
Savolitinib vs. Sunitinib in MET-driven PRCC
This study is designed for patients diagnosed with MET-driven, unresectable and locally advanced or metastatic Papillary Renal Cell Carcinoma. The purpose of this study is to see if an investigatio...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-301
Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors
This research study is studying a combination of drugs as a possible treatment for rare genitourinary malignancies. -The names of the study drugs involved in this study are: - Nivolumab - Ipilimumab
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-423
The purpose of this study is to determine whether an investigational immunotherapy nivolumab in combination with ipilimumab or in combination with standard of care chemotherapy is more effective th...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-275
The purpose of this study is to determine whether Nivolumab Combined with Cabozantinib is safe and effective compared to Sunitinib in previously untreated advanced or metastatic renal cell carcinoma
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-397
Phase II trial of nivolumab in 120 treatment naïve patients with ccRCC.
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-508
This is a multicenter Phase 1b, open-label study to assess safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of cabozantinib taken in combination with atezolizumab in subjects w...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 17-492
Pembrolizumab in Treating Patients With Locally Advanced Bladder Cancer
This randomized phase III trial studies how well pembrolizumab works in treating patients with bladder cancer that has spread from where it started to nearby tissue or lymph nodes. Monoclonal antib...
Diagnosis: Kidney Cancer
Phase:
Protocol Number: 18-703
