Header

Kidney Cancer Clinical Trials

Category:Adult
Status:Active

Displaying all 16 trials

A Study to Compare Tivozanib Hydrochloride to Sorafenib in Subjects With Refractory Advanced RCC

This is a Phase 3, open-label, randomized, controlled, multi-national, multi-center, parallel-arm study comparing tivozanib to sorafenib in subjects with refractory advanced renal cell carcinoma (R...

Diagnosis: Kidney Cancer

Phase: 3

Protocol Number:

A Study of Avelumab With Axitinib Versus Sunitinib In Advanced Renal Cell Cancer (JAVELIN Renal 101)

This is a phase 3 randomized trial evaluating the anti-tumor activity and safety of avelumab in combination with axitinib and of sunitinib monotherapy, administered as first-line treatment, in pati...

Diagnosis: Kidney Cancer

Phase: 3

Protocol Number: 16-209

Study of Dalantercept and Axitinib in Patients With Advanced Renal Cell Carcinoma

The purpose of Part 1 of this study is to evaluate the safety and tolerability of dalantercept in combination with axitinib in patients with advanced renal cell carcinoma (RCC) to determine the rec...

Diagnosis: Kidney Cancer

Phase: 2

Protocol Number:

A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma

CyberKnife Based Radiosurgery is a way to deliver large doses of radiation very accurately to a tumor. The ability of this technology to minimize radiation dose to organs adjacent to the target tum...

Diagnosis: Kidney Cancer

Phase: 2

Protocol Number: 12-235

Study of Atezolizumab + Bevacizumab in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma

This research study is studying the combination of Atezolizumab and Bevacizumab as a possible treatment for Advanced Non-Clear Cell Kidney Cancer.

Diagnosis: Kidney Cancer

Phase: 2

Protocol Number: 15-592

A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Advanced or Metastatic Renal Cell Carcinoma

This is a study to determine the safety of CDX-014 and effectiveness (how well the drug works).

Diagnosis: Kidney Cancer

Phase: 1 / 2

Protocol Number: 16-297

A Phase III Study of Atezolizumab Treatment Versus Observation as Adjuvant Therapy in Patients With PD-L1 Positive, High Risk Muscle Invasive Bladder Cancer After Cystectomy [IMvigor010]

This study is to evaluate the efficacy and safety of adjuvant treatment with Atezolizumab compared with observation in participants with PD-L1-selected muscle-invasive bladder cancer (MIBC) who are...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 15-331

Trial of X4P-001 in Patients With Advanced Renal Cell Carcinoma

The purpose of the study is to test different doses of X4P-001 given alone and in combination with axitinib in patients diagnosed with advanced renal cell carcinoma. The goals of the study are to d...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 15-529

A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma

The purpose of this study is to evaluate the progression free survival (PFS), based on investigator radiologic review, of AGS-16C3F compared to axitinib in subjects with metastatic renal cell carci...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 15-569

Addition of X4P-001 to Nivolumab Treatment in Patients With Renal Cell Carcinoma

The purpose of this study is to determine if the combination of X4P-001 plus nivolumab is safe and tolerable. Secondly, the study will investigate if adding X4P-001 to nivolumab treatment has an ef...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 16-375

Study of Pembrolizumab (MK-3475) Monotherapy in Locally Advanced/Metastatic Renal Cell Carcinoma (MK-3475-427/KEYNOTE-427)

The purpose of this study is to assess the safety and efficacy of monotherapy pembrolizumab (MK-3475) in participants with renal cell carcinoma (RCC). There will be two cohorts in this study: Cohor...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 16-480

A Study Of Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100)

The main purpose of this study is to compare maintenance treatment with avelumab plus best supportive care (BSC) with BSC alone, to determine if avelumab has an effect on survival in patients with ...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 16-302

A Phase 2 Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Non Clear Cell Renal Cell Carcinoma (nccRCC) Who Have Not Received Any Chemotherapy for Advanced Disease

This is a single-arm, multicenter, Phase 2 study of lenvatinib in combination with everolimus in participants with unresectable advanced or metastatic non clear cell renal cell carcinoma (nccRCC) w...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 17-035

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

This randomized phase III trial compares nephrectomy (surgery to remove a kidney or part of a kidney) with or without nivolumab in treating patients with kidney cancer that is limited to a certain ...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 17-704

Study of TAK-228 In Patients With Previously Treated Metastatic Renal Cell Carcinoma

This research study is investigating a drug as a possible treatment for metastatic renal cell carcinoma. The intervention involved in this study is TAK-228.

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 16-527

Lenvatinib/Everolimus or Lenvatinib/Pembrolizumab Versus Sunitinib Alone as Treatment of Advanced Renal Cell Carcinoma

This is a multicenter, randomized, open-label, Phase 3 study to compare the efficacy and safety of lenvatinib in combination with everolimus (Arm A) or pembrolizumab (Arm B) versus sunitinib (Arm C...

Diagnosis: Kidney Cancer

Phase:

Protocol Number: 17-038

'