Category:Adult
Status:Active
Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors
The purpose of the study is to: - Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors - Assess...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase: 3
Protocol Number: 06-700
GVAX vs. Placebo for MDS/AML After Allo HSCT
This research study is a Phase II clinical trial. Phase II clinical trials test the effectiveness of an investigational intervention to learn whether the intervention, in this case, the GVAX vaccin...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase: 2
Protocol Number: 12-217
Meloxicam vs Placebo for Mobilization
This research study is evaluating a drug called meloxicam to see if it provides a benefit to people receiving Autologous Hematopoietic Stem Cell Transplantation (AHSCT). The participant is currentl...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase: 2
Protocol Number: 13-195
National Marrow Donor Program Long-Term Donor Follow-Up
This is an observational study of unstimulated bone marrow (BM) and filgrastim-mobilized peripheral blood stem cell (PBSC) donors. The primary goal is to evaluate the hypothesis that the incidence ...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase: N/A
Protocol Number: 10-704
Allo vs Hypomethylating/Best Supportive Care in MDS (BMT CTN 1102)
This study is designed as a multicenter trial, with biological assignment to one of two study arms; Arm 1: Reduced intensity conditioning allogeneic hematopoietic cell transplantation (RIC-alloHCT)...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase: N/A
Protocol Number: 13-453
This research study is evaluating the feasibility and impact of an intervention to improve sexual function in stem cell transplant survivors on participants' sexual function, quality of life, ...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase: N/A
Protocol Number: 15-158
This is a multicenter prospective collection of leftover respiratory tract secretions, paired blood and NP swabs, and clinical circumstances from pediatric HCT patients, followed by next generation...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-113
The purpose of this study is to compare the efficacy and safety of maribavir to valganciclovir for the treatment of cytomegalovirus (CMV) infection in asymptomatic hematopoietic stem cell transplan...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-081
Shared Care: Patient-Centered Management After Hematopoietic Cell Transplantation
This research study aims to evaluate the effectiveness of allowing patients who have had a hematopoietic cell transplant to receive some of their post-transplant care with a local oncologist rather...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-253
Psychological Intervention for Caregivers of Patients Undergoing Stem Cell Transplant
This research study is evaluating the impact of a psychological intervention on the quality of life and mood of caregivers of patients undergoing stem cell transplant.
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-476
The purpose of this study is to compare relapse-free survival between participants with FLT3/ITD AML in first morphologic complete remission (CR1) who undergo hematopoietic stem cell transplant (HC...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-421
Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies
This study is a Phase 1, Non-randomized, Open-label/Phase 2 Randomized, Blinded Study of ProTmune (ex vivo programmed mobilized peripheral blood cells) Versus Non-programmed mobilized peripheral bl...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-387
Patients receiving high-dose chemotherapy/conditioning prior to stem cell transplantation (SCT) are at high risk for developing painful lesions in the oral cavity, known as oral mucositis (OM). In ...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-458
Ruxolitinib Pre-, During- and Post-HSCT for Patients With Primary or Secondary Myelofibrosis.
This research study is studying a drug called Ruxolitinib as a possible treatment for Myelofibrosis.
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-569
The goal of this research study is to find out if a novel phone-based positive psychology intervention that focuses on improving health behaviors and positive emotions can help improve mood, health...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 18-225
This study is to compare the efficacy and safety of defibrotide prophylaxis in addition to best supportive care versus best supportive care alone in the prevention of hepatic veno- occlusive diseas...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 17-654
This research study is studying the removal of a subset of white blood cells (called alpha/beta T cells) from the donor product using a cell separation device before the product is transplanted int...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 18-270
Letermovir Treatment for Refractory or Resistant Cytomegalovirus Infection
The trial will evaluate the safety and efficacy of letermovir antiviral treatment of active cytomegalovirus infection or cytomegalovirus disease in patients with infections that are refractory or r...
Diagnosis: Hematopoietic Stem Cell Transplant, Pediatric Hematopoietic Stem Cell Transplant (HSCT)
Phase:
Protocol Number: 18-348
This is a multi-center study to evaluate the safety, tolerability, PK, PD, and clinical activity of EQ001 in subjects with Acute Graft Versus Host Disease (aGVHD).
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 18-647
In this research study, our main goal for the ipilimumab portion of the study is to determine the highest dose of ipilimumab that can be given safely in several courses and to determine what side e...
Diagnosis: Hematopoietic Stem Cell Transplant
Phase:
Protocol Number: 19-142