Hematopoietic Stem Cell Transplant Clinical Trials

Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

The purpose of the study is to: - Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors - Assess...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 3

Protocol Number: 06-700

GVAX vs. Placebo for MDS/AML After Allo HSCT

This research study is a Phase II clinical trial. Phase II clinical trials test the effectiveness of an investigational intervention to learn whether the intervention, in this case, the GVAX vaccin...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 2

Protocol Number: 12-217

Meloxicam vs Placebo for Mobilization

This research study is evaluating a drug called meloxicam to see if it provides a benefit to people receiving Autologous Hematopoietic Stem Cell Transplantation (AHSCT). The participant is currentl...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 2

Protocol Number: 13-195

Presatovir in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus Infection of the Upper Respiratory Tract

This study will evaluate the effect of presatovir on respiratory syncytial virus (RSV) viral load in autologous or allogeneic hematopoietic cell transplant (HCT) recipients with an acute RSV upper ...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 2

Protocol Number: 14-473

Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant

This randomized phase II trial studies the safety and how well multi-peptide cytomegalovirus (CMV)-modified vaccinia Ankara (MVA) vaccine works in reducing CMV complications in patients previously ...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 2

Protocol Number: 15-555

Fecal Microbiota Transplantation After HSCT

This research study is studying an intervention called fecal microbiota transplantation (FMT). Patients who are scheduled to undergo Hematopoietic Stem Cell Transplantation are invited to take part...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 0

Protocol Number: 16-023

National Marrow Donor Program Long-Term Donor Follow-Up

This is an observational study of unstimulated bone marrow (BM) and filgrastim-mobilized peripheral blood stem cell (PBSC) donors. The primary goal is to evaluate the hypothesis that the incidence ...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: N/A

Protocol Number: 10-704

Allo vs Hypomethylating/Best Supportive Care in MDS (BMT CTN 1102)

This study is designed as a multicenter trial, with biological assignment to one of two study arms; Arm 1: Reduced intensity conditioning allogeneic hematopoietic cell transplantation (RIC-alloHCT)...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: N/A

Protocol Number: 13-453

A Multimodal Intervention to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors

This research study is evaluating the feasibility and impact of an intervention to improve sexual function in stem cell transplant survivors on participants' sexual function, quality of life, a...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: N/A

Protocol Number: 15-158

Psychological Intervention for Caregivers of Patients Undergoing Hematopoietic Stem Cell Transplantation (HCT)

This research study is evaluating a psychological intervention for caregivers of patients undergoing stem cell transplantation. Phase 1 will include a qualitative phase to refine the intervention t...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 16-522

Pasireotide in Prevention of GI Toxicity

The purpose of this study is to evaluate if the drug, Pasireotide, is safe and effective in reducing the gastrointestinal side effects of the drugs received to prepare for allogeneic stem cell tran...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 16-328

Pathogen Identification in Pediatric Hematopoietic Stem Cell Transplant Patients With Suspected Lower Respiratory Tract Infection

This is a multicenter prospective collection of leftover respiratory tract secretions, paired blood and NP swabs, and clinical circumstances from pediatric HCT patients, followed by next generation...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-113

Study for the Treatment of Cytomegalovirus (CMV) Infection in Hematopoietic Stem Cell Transplant Recipients

The purpose of this study is to compare the efficacy and safety of maribavir to valganciclovir for the treatment of cytomegalovirus (CMV) infection in asymptomatic hematopoietic stem cell transplan...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-081

Shared Care: Patient-Centered Management After Hematopoietic Cell Transplantation

This research study aims to evaluate the effectiveness of allowing patients who have had a hematopoietic cell transplant to receive some of their post-transplant care with a local oncologist rather...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-253