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Hematopoietic Stem Cell Transplant Clinical Trials

Category:Adult
Status:Active

Displaying all 15 trials

Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

The purpose of the study is to: - Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors - Assess...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 3

Protocol Number: 06-700

GVAX vs. Placebo for MDS/AML After Allo HSCT

This research study is a Phase II clinical trial. Phase II clinical trials test the effectiveness of an investigational intervention to learn whether the intervention, in this case, the GVAX vaccin...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 2

Protocol Number: 12-217

Meloxicam vs Placebo for Mobilization

This research study is evaluating a drug called meloxicam to see if it provides a benefit to people receiving Autologous Hematopoietic Stem Cell Transplantation (AHSCT). The participant is currentl...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 2

Protocol Number: 13-195

Fecal Microbiota Transplantation After HSCT

This research study is studying an intervention called fecal microbiota transplantation (FMT). Patients who are scheduled to undergo Hematopoietic Stem Cell Transplantation are invited to take part...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: 0

Protocol Number: 16-023

National Marrow Donor Program Long-Term Donor Follow-Up

This is an observational study of unstimulated bone marrow (BM) and filgrastim-mobilized peripheral blood stem cell (PBSC) donors. The primary goal is to evaluate the hypothesis that the incidence ...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: N/A

Protocol Number: 10-704

Allo vs Hypomethylating/Best Supportive Care in MDS (BMT CTN 1102)

This study is designed as a multicenter trial, with biological assignment to one of two study arms; Arm 1: Reduced intensity conditioning allogeneic hematopoietic cell transplantation (RIC-alloHCT)...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: N/A

Protocol Number: 13-453

A Multimodal Intervention to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors

This research study is evaluating the feasibility and impact of an intervention to improve sexual function in stem cell transplant survivors on participants' sexual function, quality of life, a...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase: N/A

Protocol Number: 15-158

Pathogen Identification in Pediatric Hematopoietic Stem Cell Transplant Patients With Suspected Lower Respiratory Tract Infection

This is a multicenter prospective collection of leftover respiratory tract secretions, paired blood and NP swabs, and clinical circumstances from pediatric HCT patients, followed by next generation...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-113

Study for the Treatment of Cytomegalovirus (CMV) Infection in Hematopoietic Stem Cell Transplant Recipients

The purpose of this study is to compare the efficacy and safety of maribavir to valganciclovir for the treatment of cytomegalovirus (CMV) infection in asymptomatic hematopoietic stem cell transplan...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-081

Shared Care: Patient-Centered Management After Hematopoietic Cell Transplantation

This research study aims to evaluate the effectiveness of allowing patients who have had a hematopoietic cell transplant to receive some of their post-transplant care with a local oncologist rather...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-253

Psychological Intervention for Caregivers of Patients Undergoing Stem Cell Transplant

This research study is evaluating the impact of a psychological intervention on the quality of life and mood of caregivers of patients undergoing stem cell transplant.

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-476

A Trial of the FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor Gilteritinib Administered as Maintenance Therapy Following Allogeneic Transplant for Patients With FLT3/Internal Tandem Duplication (ITD) Acute Myeloid Leukemia (AML)

The purpose of this study is to compare relapse-free survival between participants with FLT3/ITD AML in first morphologic complete remission (CR1) who undergo hematopoietic stem cell transplant (HC...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-421

Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies

This study is a Phase 1, Non-randomized, Open-label/Phase 2 Randomized, Blinded Study of ProTmune (ex vivo programmed mobilized peripheral blood cells) Versus Non-programmed mobilized peripheral bl...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-387

Gelclair at Conditioning or After Oral Mucositis Diagnosed vs. Magic Mouth Wash in Stem Cell Transplant Recipients

Patients receiving high-dose chemotherapy/conditioning prior to stem cell transplantation (SCT) are at high risk for developing painful lesions in the oral cavity, known as oral mucositis (OM). In ...

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-458

Ruxolitinib Pre-, During- and Post-HSCT for Patients With Primary or Secondary Myelofibrosis.

This research study is studying a drug called Ruxolitinib as a possible treatment for Myelofibrosis.

Diagnosis: Hematopoietic Stem Cell Transplant

Phase:

Protocol Number: 17-569

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