Pediatric Neuroblastoma Clinical Trials
Category:Pediatric
Status:Active
Displaying all 8 trials
131I-MIBG Alone VS. 131I-MIBG With Vincristine and Irinotecan VS131I-MIBG With Vorinistat
This study will compare three treatment regimens containing metaiodobenzylguanidine (MIBG) and compare their effects on tumor response and associated side effects, to determine if one therapy is be...
Diagnosis: Pediatric Neuroblastoma
Phase: 2
Protocol Number: 14-184
This phase I trial studies the side effects and best dose of lenalidomide when given together with dinutuximab with or without isotretinoin in treating younger patients with neuroblastoma that does...
Diagnosis: Pediatric Neuroblastoma
Phase: 1
Protocol Number: 12-505
Sorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastoma
This study will combine three drugs: sorafenib, cyclophosphamide and topotecan. Adding sorafenib to cyclophosphamide and topotecan may increase the effectiveness of this combination. The investigat...
Diagnosis: Pediatric Neuroblastoma
Phase: 1
Protocol Number: 14-494
A Study of Olaratumab Alone and in Combination With Standard Chemotherapies in Children With Cancer
The main purpose of this study is to evaluate the safety of different doses of olaratumab and to determine which dose should be used for future pediatric studies. The present study is open to child...
Diagnosis: Pediatric Brain Tumor, Pediatric Solid Tumors, Pediatric Sarcoma, Pediatric Neuroblastoma
Phase: 1
Protocol Number: 16-196
Vemurafenib in Children With Recurrent/Refractory BRAFV600E-mutant Gliomas
This is a multicenter, safety and pharmacokinetic trial to determine the MTD and/or select a recommended phase 2 dose (RP2D) of vemurafenib in children with recurrent or refractory gliomas containi...
Diagnosis: Pediatric Neuroblastoma
Phase: 0
Protocol Number: 16-234
This research trial studies biomarkers in tumor tissue samples from patients with newly diagnosed neuroblastoma or ganglioneuroblastoma. Studying samples of tumor tissue from patients with cancer i...
Diagnosis: Pediatric Neuroblastoma
Phase: N/A
Protocol Number: 00-272
This phase III trial studies how well response and biology-based risk factor-guided therapy works in treating younger patients with non-high risk neuroblastoma. Sometimes a tumor may not need treat...
Diagnosis: Pediatric Neuroblastoma
Phase:
Protocol Number: 14-449
This proposal sets forth the platform for a Precision Medicine clinical trial through the New Approaches to Neuroblastoma Therapy (NANT) consortium. The plan is to utilize NANT's established mu...
Diagnosis: Pediatric Neuroblastoma
Phase:
Protocol Number: 16-624
