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Radiation Oncology Clinical Trials

Category:Adult
Status:Active

Displaying all 16 trials

Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer

The purpose of this study is to determine the effectiveness of enzalutamide as part of adjuvant androgen deprivation therapy (ADT) with a luteinizing hormone releasing hormone analogue (LHRHA) in m...

Diagnosis: Prostate Cancer, Radiation Oncology

Phase: 3

Protocol Number: 15-038

Randomized Trial of Intensity-Modulated Proton Beam Therapy (IMPT) Versus Intensity-Modulated Photon Therapy (IMRT) for the Treatment of Oropharyngeal Cancer of the Head and Neck

The goal of this clinical research study is to compare the side effects of 2 radiation treatments for head and neck cancer. The 2 treatments are intensity modulated photon therapy (IMRT) and intens...

Diagnosis: Head and Neck Cancer, Radiation Oncology

Phase: 2 / 3

Protocol Number: 16-155

Phase II Study of Proton Radiation Therapy for Neuroblastoma

This research study is evaluating a therapy called proton beam radiation therapy (PBRT) as a possible treatment for neuroblastoma. Neuroblastoma most commonly occurs in and around the adrenal gland...

Diagnosis: Radiation Oncology

Phase: 2

Protocol Number: 13-443

Phase II Protocol Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone

This research study is studying a form of radiation therapy called stereotactic body radiation therapy or SBRT as a possible treatment for Cancer that has spread to the spine or other bone

Diagnosis: Radiation Oncology

Phase: 2

Protocol Number: 16-207

Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors

This research study is studying stereotactic body radiotherapy (SBRT) as a possible treatment for lung relapse of Ewing Sarcoma, Rhabdomyosarcoma, or Wilms Tumor. SBRT is a form of targeted radioth...

Diagnosis: Radiation Oncology, Pediatric Sarcoma

Phase: 1 / 2

Protocol Number: 15-278

NBTXR3 Nanoparticles and EBRT or EBRT With Brachytherapy in the Treatment of Prostate Adenocarcinoma

This study is a Phase 1/2 open-label involving 2 groups of patients newly diagnosed with either unfavorable intermediate risk or high risk prostate adenocarcinoma. One group will receive only EBRT ...

Diagnosis: Radiation Oncology, Prostate Cancer

Phase: 1 / 2

Protocol Number: 16-445

Study Evaluating a Stereotactic Boost/Treatment for Recurrent or Metastatic Cancer of the Head and Neck

This research study seeks to gain new knowledge about the addition of a carefully targeted "boost" dose of radiation as a possible treatment for recurrent or metastatic head or neck cance...

Diagnosis: Head and Neck Cancer, Radiation Oncology

Phase: 1

Protocol Number: 15-183

Whole Brain Radiation Versus Stereotactic Radiation (SRS) in Patients With 5-15 Brain Metastases: A Phase III, Randomized Clinical Trial

This research study is studying two different types of radiation as treatment for brain metastases (tumors in the brain that spread from a cancer that originated elsewhere in the body)

Diagnosis: Radiation Oncology

Phase:

Protocol Number: 16-305

Proton Craniospinal Irradiation With Bone Sparing to Decrease Growth Decrement From Radiation

This research study is studying proton radiation as a possible treatment for brain tumor that requires radiation. The radiation involved in this study is: -Proton Radiation

Diagnosis: Radiation Oncology

Phase:

Protocol Number: 17-283

Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-6 Brain Metastases

This research study is studying stereotactic radiation (focused/pinpoint radiation that targets each individual tumor but not the surrounding brain) instead of whole-brain radiation (radiation targ...

Diagnosis: Radiation Oncology, Lung Cancer

Phase:

Protocol Number: 17-550

Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis

The purpose of this study is to find out what effects, good and/or bad, the drug nintedanib in combination with steroids, has on the lungs. Furthermore, such treatments' side effects will be st...

Diagnosis: Radiation Oncology

Phase:

Protocol Number: 17-360

Preoperative vs Postoperative IMRT for Extremity/Truncal STS

This study is designed to determine if preoperative image guided radiation therapy (IGRT) delivered using intensity modulated radiation therapy (IMRT) followed by surgery results in similar short-t...

Diagnosis: Radiation Oncology

Phase:

Protocol Number: 17-668

Atezolizumab Immunotherapy in Patients With Advanced NSCLC

Phase II trial of induction immunotherapy with atezolizumab for patients with unresectable stage IIIA and IIIB NSCLC eligible for chemoradiotherapy with curative intent.

Diagnosis: Radiation Oncology

Phase:

Protocol Number: 17-474

Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)

This research study is comparing two different combinations of androgen deprivation therapy (ADT) used together with radiation as a treatment for rising PSA after radical prostatectomy (prostate ca...

Diagnosis: Prostate Cancer, Radiation Oncology

Phase:

Protocol Number: 16-623

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

This randomized phase II clinical trial studies the side effects and how well proton beam or intensity-modulated radiation therapy works in preserving brain function in patients with IDH mutant gra...

Diagnosis: Radiation Oncology, Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 18-711

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

This study will test an investigational drug called AZD1390 in combination with radiation therapy for the treatment of brain tumors. This is the first time AZD1390 is being given to patients. This ...

Diagnosis: Brain/Neuro Cancer: Newly Diagnosed, Radiation Oncology

Phase:

Protocol Number: 18-018

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