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Brain/Neuro Cancer: Recurrent Glioblastoma Clinical Trials

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Displaying all 13 trials

FMISO PET Study of Glioblastoma

In this research study, the investigators are using FMISO-PET and MRI scans to explore the delivery of bevacizumab to the blood vessels in patient's with recurrent glioblastoma before and after...

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase: 2

Protocol Number: 13-482

Oral ONC201 in Adult Recurrent Glioblastoma

ONC201 is a new drug candidate that kills cancer cells but not normal cells in laboratory studies and successfully completed a phase I clinical trial in advanced cancer patients. This clinical tria...

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase: 2

Protocol Number: 15-318

Anti-LAG-3 or Urelumab Alone and in Combination With Nivolumab in Treating Patients With Recurrent Glioblastoma

This phase I trial studies the safety and best dose of anti-LAG-3 (anti-LAG-3 monoclonal antibody BMS-986016) or urelumab alone and in combination with nivolumab in treating patients with glioblast...

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase: 1

Protocol Number:

Bevacizumab w / Temozolomide PET & Vascular MRI For GBM

This research study is exploring how the blood vessels in the participant's tumor change from treatment with bevacizumab, and how these changes affect the way their tumor absorbs temozolomide (...

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase: N/A

Protocol Number: 13-322

TORC1/2 Inhibitor INK128 Before and After Surgery in Treating Patients With Recurrent Glioblastoma

This partially randomized pilot trial studies how much TORC1/2 inhibitor INK128 reaches the brain tumor and how well it works when given before and after surgery in treating patients with glioblast...

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase: N/A

Protocol Number: 14-095

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma

This research study involves two investigational drugs, veledimex, an activator ligand (INXN-1001) in combination with an Adenovirus Vector Engineered to Express hIL-12 (INXN-2001). IL-12 is a prot...

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase:

Protocol Number: 14-339

A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)

A Phase 1b/2, multicenter, open-label study designed to evaluate the efficacy and safety of ACP-196 in subjects with recurrent GBM who have progressed after 1 or 2 prior systemic treatment regimens.

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase:

Protocol Number: 15-523

A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)

This is a Phase 1/2, open label study that will be conducted in 2 parts. The first part of the study (Phase 1) will consist of a dose-escalation assessment of the safety and tolerability of epacado...

Diagnosis: Head and Neck Cancer, Brain/Neuro Cancer: Recurrent Glioblastoma, Lung Cancer, GYN: Ovarian, Fallopian, Peritoneal Cancer

Phase:

Protocol Number: 15-484

First in Patient Study for PF-06840003 in Malignant Gliomas

This study will evaluate the safety and tolerability of increases doses of PF-06840003 in patients with malignant gliomas.

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase:

Protocol Number: 16-358

Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma

This is a multicenter, Phase 2 study to assess the activity of tesevatinib in patients with recurrent glioblastoma.

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase:

Protocol Number: 16-467

A Study of Abemaciclib in Recurrent Glioblastoma

This research study is studying a targeted therapy as a possible treatment for recurrent glioblastoma (GBM). The following intervention will be used in this study: -Abemaciclib

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase:

Protocol Number: 16-383

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

This pilot clinical trial studies how well lapatinib ditosylate before surgery works in treating patients with high-grade glioma that has come back after a period of time during which the tumor cou...

Diagnosis: Brain/Neuro Cancer: Recurrent Glioblastoma

Phase:

Protocol Number: 14-297

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