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Brain/Neuro Cancer: Other Non-Glioblastoma Clinical Trials

Category:Adult
Status:Active

Displaying all 14 trials

ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases

The purpose of this research study is to determine the effects (good and bad) of ZK219477(sagopilone) on participants and their cancer. ZK219477 is a chemotherapy drug that is thought to work by in...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma, Breast: Metastatic

Phase: 2

Protocol Number: 06-268

A Study of Nivolumab in Adult Participants With Recurrent High-Grade Meningioma

This research study is studying a targeted immunotherapy as a possible treatment for Recurrent Meningioma. The name of the study intervention involved in this study is Nivolumab.

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: 2

Protocol Number: 15-490

Pembrolizumab In Central Nervous System Metastases

This research study is studying Pembrolizumab as a possible treatment for this diagnosis for metastases in the central nervous system (brain and spinal cord).

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: 2

Protocol Number: 16-153

Palbociclib In Progressive Brain Metastases

This research study is studying palbociclib as a possible treatment for recurrent brain metastases. - Pfizer, a pharmaceutical company, is supporting this research study by providing the study drug...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: 2

Protocol Number: 16-254

Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1

The purpose of this research study is to determine if ranibizumab can prevent the growth of neurofibromas. We will also be collecting extra blood and serum samples to help us learn more about NF1. ...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: N/A

Protocol Number: 07-332

Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype

The purpose of this study is to test if the study drug called pembrolizumab could control the growth or shrink the cancer but it could also cause side effects. Researchers hope to learn if the stud...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: N/A

Protocol Number: 16-530

Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients

The purpose of this study is to compare the efficacy and safety of eflornithine in combination with lomustine, compared to lomustine taken alone, in treating patients whose anaplastic astrocytoma h...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 16-517

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2

This research study is evaluating an investigational drug called rQNestin34.5v.2. This research study is a Phase I clinical trial, which tests the safety of an investigational drug and also tries t...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 16-557

Phase II Study Of Vistusertib (AZD2014) For Recurrent Grade II-III Meningiomas

This research study is studying a chemotherapy as a possible treatment for Meningiomas (recurrent). The study intervention involved in this study is: --AZD2014 (vistusertib)

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 16-563

Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy

This research study is studying Proton Radiation as a possible treatment for brain tumor. The radiation involved in this study is: -Proton Radiation

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 17-250

Phase II Trial of Pembrolizumab in Recurrent or Residual High Grade Meningioma

This research study is studying a drug as a possible treatment for High Grade Meningioma. The drug involved in this study is an immunotherapy drug called pembrolizumab

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 17-296

Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma

This phase II trial studies how well vemurafenib and cobimetinib work in treating patients with BRAF V600E mutation positive craniopharyngioma. Vemurafenib and cobimetinib may stop the growth of tu...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 17-722

Study of AG-120 and AG-881 in Subjects With Low Grade Glioma

Study to evaluate the suppression of 2-HG (2-hydroxyglutarate) in IDH-1 mutant gliomas in resected tumor tissue following pre-surgical treatment with AG-120 or AG-881.

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 17-631

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

This randomized phase II clinical trial studies the side effects and how well proton beam or intensity-modulated radiation therapy works in preserving brain function in patients with IDH mutant gra...

Diagnosis: Radiation Oncology, Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 18-711

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