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Brain/Neuro Cancer: Other Non-Glioblastoma Clinical Trials

Category:Adult
Status:Active

Displaying all 11 trials

ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases

The purpose of this research study is to determine the effects (good and bad) of ZK219477(sagopilone) on participants and their cancer. ZK219477 is a chemotherapy drug that is thought to work by in...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma, Breast: Metastatic

Phase: 2

Protocol Number: 06-268

A Study of Nivolumab in Adult Participants With Recurrent High-Grade Meningioma

This research study is studying a targeted immunotherapy as a possible treatment for Recurrent Meningioma. The name of the study intervention involved in this study is Nivolumab.

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: 2

Protocol Number: 15-490

AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas

The goal of this clinical research study is to learn if the study drug AZD2014 can shrink growing or symptomatic meningiomas.

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: 2

Protocol Number: 15-590

Pembrolizumab In Central Nervous System Metastases

This research study is studying Pembrolizumab as a possible treatment for this diagnosis for metastases in the central nervous system (brain and spinal cord).

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: 2

Protocol Number: 16-153

Palbociclib In Progressive Brain Metastases

This research study is studying palbociclib as a possible treatment for recurrent brain metastases. - Pfizer, a pharmaceutical company, is supporting this research study by providing the study drug...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: 2

Protocol Number: 16-254

Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1

The purpose of this research study is to determine if ranibizumab can prevent the growth of neurofibromas. We will also be collecting extra blood and serum samples to help us learn more about NF1. ...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: N/A

Protocol Number: 07-332

Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype

The purpose of this study is to test if the study drug called pembrolizumab could control the growth or shrink the cancer but it could also cause side effects. Researchers hope to learn if the stud...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase: N/A

Protocol Number: 16-530

Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas

The primary objective is to estimate the proportions of vestibular schwannomas (VS) and meningiomas after 10 days of exposure to the study drug RAD001 at a dose of 10 mg daily, as determined by imm...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 14-520

Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard Therapy

PURPOSE The drug Lapatinib has been shown to inhibit both epidermal growth factor receptor (EGFR) and erbB2 tyrosine kinases resulting in an effective slowing of disease progression in breast cance...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 14-499

Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients

The purpose of this study is to compare the efficacy and safety of eflornithine in combination with lomustine, compared to lomustine taken alone, in treating patients whose anaplastic astrocytoma h...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 16-517

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2

This research study is evaluating an investigational drug called rQNestin34.5v.2. This research study is a Phase I clinical trial, which tests the safety of an investigational drug and also tries t...

Diagnosis: Brain/Neuro Cancer: Other Non-Glioblastoma

Phase:

Protocol Number: 16-557

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