9 Head and Neck Cancer 1 1 0 9 9 36 http://clinicaltrials.dfhcc.harvard.edu/trials/36 Study of IMC-A12, Alone or in Combination With Cetuximab, in Patients With Recurrent or Metastatic Squamous Cell Carcinoma (MSCC) of the Head and Neck The purpose of this study is to determine if IMC-A12 alone or in combination with Erbitux can increase survival in patients with Squamous Cell Carcinoma Head and Neck Cancer who have had disease progression after treatment with chemotherapeutic platinum drugs. Recruiting 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer Phase 2 44 http://clinicaltrials.dfhcc.harvard.edu/trials/44 A Phase II Study of Epstein-Barr Virus-Specific Immunotherapy for Nasopharyngeal Carcinoma The purpose of this research study is to determine how effective and how safe it is to give an Epstein-Barr Virus (EBV) immunotherapy product to participants with nasopharyngeal carcinoma (NPC) associated with EBV that has come back or spread to other parts of the participants body. The EBV immunotherapy product will be made with white blood cells from the participants blood and takes about 16 weeks to create. This EBV immunotherapy product may stop cancer cells from growing and cause the tumors to disappear. Recruiting 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer Phase 2 118 http://clinicaltrials.dfhcc.harvard.edu/trials/118 Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma Photon beam radiation is the standard type of radiation used to treat nasopharyngeal carcinoma. Photon beam radiation enters the body and passes through healthy tissue, encounters the tumor and leaves the body through healthy tissue. Proton beam radiation has been shown to have the same effect on tumors as photon beam radiation but it enters the body, passes through healthy tissue, and encounters the tumor but then stops. This means less healthy tissue is affected by proton beam treatment than by photon beam treatment. The purpose of this study is to determine the effectiveness of proton beam radiation in treating nasopharyngeal cancer and reducing the acute and long-term side effects from the treatment. This study will also test to see if the sparing of the healthy tissue can improve quality of life Recruiting 8 Esophageal Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/8-esophageal-cancer 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer Phase 2 1148 http://clinicaltrials.dfhcc.harvard.edu/trials/1148 AZD2171 in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer RATIONALE: AZD2171 may stop the growth of head and neck cancer by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well AZD2171 works in treating patients with recurrent or newly diagnosed metastatic head and neck cancer. Recruiting 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer Phase 2 286 http://clinicaltrials.dfhcc.harvard.edu/trials/286 Abraxane in Combination With Carboplatin, Erbitux and IMRT for Locally Advanced Squamous Cancer of the Head and Neck The purpose of the Phase I part of this research study is to determine the safest and most effective dose of Abraxane when given in combination with carboplatin and Erbitux during radiation therapy for head and neck cancer. The purpose of the Phase II part of this study is to determine the effects of the treatment on head and neck cancers, as well as to further study the safety of this treatment. Recruiting 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer Phase 1/Phase 2 1164 http://clinicaltrials.dfhcc.harvard.edu/trials/1164 Study to Assess Safety and Tolerability of AG013 in Oral Mucositis in Subjects Receiving Induction Chemotherapy for the Treatment of Cancers of the Head and Neck The purpose of this study is to assess the safety and tolerability of AG013 (genetically modified L. lactis bacteria engineered to secrete human Trefoil Factor 1), and to explore the ability of AG013 to attenuate the course and severity of oral mucositis (OM) in subjects receiving induction chemotherapy for the treatment of head and neck cancer. Recruiting 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer Phase 1/Phase 2 1382 http://clinicaltrials.dfhcc.harvard.edu/trials/1382 Panitumumab Plus Chemoradiotherapy and Induction Chemotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck This study is being done to test whether panitumumanb, in combination with chemotherapy and radiation is safe in people with head and neck cancer. Another goal of this study is to find the highest dose of the study drugs that can be given safely without causing serious sife effects. Panitumumab is a type of drug called a monoclonal antibody that has been studied in other types of cancers, such as kidney and colon. This monoclonal antibody is directed against the epidermal growth factor receptor (EGFR). EGFR has been found on the majority of head and neck cancer cells. By blocking EGFR, this monoclonal antibody may inhibit the growth of head and neck cancer cells. Recruiting 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer Phase 1 205 http://clinicaltrials.dfhcc.harvard.edu/trials/205 A Pilot Study of Acupuncture Treatment for Dysphagia This study is a pilot randomized, sham-controlled trial of acupuncture for Head and Neck Cancer patients with dysphagia after chemoradiation therapy. The study will assess the feasibility of recruiting and retaining head and neck cancer patients, will assess the feasibility of administering the acupuncture protocol as well as a series of outcome instruments and protocols, and will collect preliminary data on the efficacy and safety of acupuncture on dysphagia related symptoms and health related quality of life. Recruiting 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer N/A 1309 http://clinicaltrials.dfhcc.harvard.edu/trials/1309 Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer Patients The purpose of the investigation is to learn whether intense swallowing exercise or intense swallowing exercise coupled with electrical stimulation (E-Stim) helps patients who had head/neck cancer and currently have dysphagia swallow better. Recruiting 9 Head and Neck Cancer http://clinicaltrials.dfhcc.harvard.edu/diagnoses/9-head-and-neck-cancer